Journal de toxicologie clinique
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Abstrait

Rare side effect of linezolid, used in multiple drug resistant infections, bone marrow depression

Mine Altinkaya

Antibiotic resistant infections are an important part of serious adult infections. Increased resistance and treatment
difficulties are observed in infections caused by enterococ, staphylococcus and pneumococ. They are drugs used in
tissue infections and pneumonia. The most important side effect that limits the use of linezolid, which has a very
good clinical efficacy, is bone marrow suppression.An 82-year-old male patient was admitted to the 3rd step intensive
care unit due to bacterial pneumonia. The patient developed severe bone marrow depression symptoms during
linozolid therapy; after discontinuation of treatment, the pressure on the bone marrow was
reversible.Myelosuppression seen during and after linezolid therapy is reversible