Pédiatrie et thérapeutique
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Pregnancy-Induced Complications and Neonatal Outcome

Boskabadi Hassan, Bagheri Fatemeh*

Background and objectives: Maternal problems during pregnancy are an important and influential factor on the health status and consequences of newborns. This study was performed to compare the status of premature infants born to mothers with pregnancy problems and without pregnancy problems.

Materials and methods: This cross-sectional study examined the files of 1110 premature infants admitted to Ghaem Hospital in Mashhad from 2015 to 2022. Sampling was available in this study. After reviewing information about mothers (gestational age, maternal age, type of delivery, parity, underlying diseases, pregnancy complications, placental and membranous problems) and infant (age, height, weight, head circumference, Apgar score of the first and fifth minutes), infants were divided into two groups: mothers with and without pregnancy problems.

Results: 79.7% and 20.3% of preterm infants were in the mothers with and without medical pregnancy complications groups, respectively. Higher Maternal age and cesarean-section delivery rate were associated with medical pregnancy complications (P-value <0.001). Preeclampsia, hypertension, diabetes, and heart problems were the most prevalent complications found among our population. The first minute Apgar score, weight, height, head circumference in infants of mothers with medical pregnancy complications were lower than in another group (P-value <0.05). In addition, pregnancy complications were a significant contributor to the incidence of Premature Rupture of Membranes (PROM) (P=0.012) and Respiratory Distress Syndrome (RDS) (P=0.001).

Conclusion: This study has shown that pregnancy complications adversely pose the risk of severe consequences such as preterm delivery, cesarean section, PROM, Lower weight and gestational age and RDS. In the light of our findings, proper control of high-risk mothers may face the prospect of adverse outcomes.