Journal d'imagerie et de dynamique moléculaires
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Modern Microwave Thermometry for Breast Cancer

Sergey Vesnin, Arran K Turnbull, J Michael Dixon and Igor Goryanin*

The temperature of a malignant tumour is a universal indicator of the growth rate of the tumor. Tumor temperature can be used as a prediction of the benefit of individual therapies and in monitoring the efficacy of breast cancer treatment. This review provides a systematic analysis of the data available in the current literature on the role of microwave thermometry in risk estimation, the diagnosis of breast pathology and in assessing the effect of neoadjuvant therapy for breast cancer treatment.

Various aspects of the use of microwave thermometry in breast diseases are described: the diagnostic value of the method and the value in differentiating hyperplasia, benign and malignant disease. Research has also suggested a prognostic role of microwave thermometry and its possible application to assess the effect of preoperative chemotherapy in locally advanced breast cancer.

Microwave thermometry is a non-invasive method that can provide valuable information in relation to the diagnosis of various breast pathologies and may have value in screening programs to identify high risk groups for subsequent diagnostics using traditional methods (ultrasound, X-ray mammography, breast MRI, morphology). Microwave thermometry can also be used to assess the effect of ongoing neoadjuvant therapy of the primary nonoperative forms of breast cancer in order to allow early detection of response and provide as part of personalized medicine