Journal de toxicologie clinique
Libre accès

Abstrait

Biochemical Assessment of the Hepatic and Hematological Functions of Printing Workers

Shimaa Tarek Ahmed*, Hoda Hassan Baghdadi, Fatma Mohamady El Demerdash

Background: In the printing industry, volatile organic compounds main sources are the uses of organic solvents, fountain solutions and cleaning agents. Biological monitoring of exposure to toxic chemicals in the workplace is a fundamental tool to evaluate human health risks and to improve occupational safety.

Aims and objectives: To investigate the effects of occupational exposure to organic solvents on some hepatic and hematological parameters among printing workers.

Materials and methods: This study was conducted in local printing company with two groups; the control group included (26) male healthy volunteer donors and the second is the workers group included (26) male volunteer workers, who have been exposed to chemicals for long time (10 years). Statistical analysis was employed.

Results: Hemoglobin and the red blood cell count of workers group were significantly lower than control group while, liver transaminases and lactate dehydrogenase enzymes were found significantly higher among printing workers as compare to the control group.

Conclusions: This study observed that the printing workers developed biochemical alterations in hematological and the hepatic enzymes with time. However, regular follow-ups are required and further studies to get better insights into the results.