Journal du métabolisme des médicaments et de la toxicologie
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A Clinical Experience: A Cutaneous Leishmaniasis Case with Spontan Abortus Following To Meglumine Antimoniate Therapy

Havya Yildiz Seckin. Yalcin Bas, Zennure Takci, Akgul Arici, Sercan Sezgin and Cigdem kunt Lsler

A 27 years old female patient was diagnosed with cutaneous leishmaniasis histopathologically and received intramuscular meglumine antimoniate therapy at a dose of 20 mg/kg/day for consecutive 20 days. The base-line pretreatment complete blood count, hepatic transaminases, lipase, amylase, beta-hCG level and electrocardiogram were within normal limits. Following to the treatment-free two weeks at the control visit, the patient stated that she was 4 weeks pregnant. Gynecological follow-up was recommended to the patient but it is learned that she had spontaneous abortion one day later. We presented our experience on this case regarding possible toxicity of meglumine antimoniate treatment on fetus.