Journal d'hématologie et des maladies thromboemboliques
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Profile of People Living with HIV in Intensive Medical Care in Togo: Epidemiological and Evolutionary Aspects

Djibril MA, Ouedraogo SM, Balaka A, Tchamdja T, Djagadou K, Agbetra A

Aim: To describe both the epidemiology and prognosis of people living with HIV (PLHIV) hospitalized in intensive care. Methodology: It is a prospective cross-sectional study conducted at the CHU Sylvanus Olympio, Lomé over a period of 12 months on known HIV infected patients or patients newly diagnosed on admission, from both sexes, aged over 15 years, hospitalized during the period between January 1st and December 31st, 2011. We studied the socio-demographic parameters, the reason for hospitalization, the infections and affections found and and their evolution. Results: During our study period 124 patients (46 men and 78 women) ère selected out of 1130, i.e. a rate of 10.9%, witz a sex ratio of 0.6. The average age of our patients was 41 ± 15.5 years, ranging from 20 years to 69 years. On admission, 41% (51 patients) ère aware of their HIV-positive status, witz 30% on antiretroviral treatment. The reasons for admission ère dominâtes by altered consciousness, repetitive seizures, severe dehydration, severe anemia witz impaired general condition and paroxysmal dyspnées witz respective rates of 48.4%, 22, 6%, 12% 32% and 4.3%. The clinicat manifestations ère dominâtes by hémi corporal sensoriel motor deficit (56.7%), fever (53%) and coma (48.4%). Biologically, 83.6% had a CD4 rate below 200 elements per mm3. Anemia was severe in 32 % out of the 87% of cases of anemia. This anemia is associated witz a lymphopenia or neutropenia or thrombocytopenia in respectively 63.3%, 57.1% and 20% of cases. Creatinine and blood urea ère elevated in 20% of cases. Infections and diseases found ère dominâtes by cerebral abscesses (40%), severe anemia (32%), gastroenteritis (12%) and meningitis (11.2%). Brain abscess ère represented by toxoplasmosis in 90% of cases. Meningitis was bacterial in 5 cases (pneumococcus), fungal (Cryptococcus) in 3 cases. Overall mortality was 43% witz a higher lethality for meningitis and severe anemia.