Pédiatrie clinique : libre accès
Libre accès
ISSN: 2572-0775
ISSN: 2572-0775
Pyae Mon Thant, Tin Tin Myint, Cho Cho Oo and Thi Tar
Introduction: Colonization and subsequent bloodstream infection of the intravascular catheters is the common cause of nosocomial bloodstream infection in newborn babies. This study was performed to determine the microbial colonization of intravascular catheters inserted in newborn babies in Special Care Baby Unit (SCBU) of 550-bedded Children Hospital, Mandalay from January to September, 2015.
Methods: Eighty-four newborn babies with or without clinical sepsis were chosen as the study population and their intravascular catheters were cultured by semi quantitative (roll plate) method. Peripheral blood samples from 35 patients with clinical sepsis in the presence of intravascular catheter were cultured by conventional method. Antimicrobial susceptibility test was performed according to CLSI.
Results: The occurrence of microbial colonization was 17.9% (15/84) and no case of catheter-related bloodstream infection (CRBSI).Coagulase-negative staphylococci (CoNS) was the predominant microorganism (8/53.3%), followed by Staphylococcus aureus (5/33.3%), Enterococcus species (1/6.7%) and Enterobacter species (1/6.7%). 25% of CoNS were methicillin-resistant and methicillin-resistant Staphylococcus aureus (MRSA) was occurred in 80% of the species. Isolated Enterococcus species was resistant to cloxacillin, oxacillin and Enterobacter species was resistant to gentamicin and cefotaxime.
Conclusions: Therefore, this study elicited the occurrence of microbial colonization on inserted intravascular catheters and their susceptibility patterns which will help the pediatricians in the choice of antibiotics and will give a useful healthcare advice on the control of nosocomial bloodstream infection.