Journal de toxicologie clinique
Libre accès
ISSN: 2161-0495
ISSN: 2161-0495
Ibeh IN, Akanu N, Mkpa AM, Isitua CC, Ogefere HO1 and Ibeh NI
The Acquired Immunodeficiency Syndrome (AIDS) Pandemic continues to inflict heavy death toll on human population worldwide with no cure yet documented. The burden of the disease remains highest in the least developed nations of the world where some of the chemotherapeutic agents already developed to combat the disease may be very scarce or not affordable; thus, creating the need for search for a definitive cure which must be cheap and affordable. The present study was on a herbal remedy called DXL (Decoction X-Liquid) which was evaluated for its anti-human immunodeficiency virus potential by administering it to HIV positive cases (n=5) over a period of 30 days. The dosage was chosen by referring to the Lethal Dose Fifty (LD 50 ) established elsewhere in another study. The HIV positive individuals exposed to DXL experienced ceasation of constant frontal headaches, intense internal heat and muscular wasting within 14 days and progressing to a body weight gain of 5.5 kg and an almost doubling of the CD 4 T-Cells number from 532.17 + 15.05 cells / ml to 932.73 + 15.05 cells / ml at the end of 30 days. Exposure to DXL also enhanced mean cell haemoglobin in the HIV positive individuals. The mechanism of action of DXL may include stoppage of CD 4 T-Cells destruction and restoration of normal metabolic activities in an HIV infected person. These findings suggest that DXL may be an intervention tool in the cycle of HIV infection.