Cardiologie clinique et expérimentale

Cardiologie clinique et expérimentale
Libre accès

ISSN: 2155-9880

Abstrait

Challenges and Strategies in Anticoagulation Management for DOAC-Treated Patients Undergoing Emergency Cardiac and Aortic Surgeries

Kohei Nagashima*

Effective anticoagulation management with heparin is critical during Cardiopulmonary Bypass (CPB) in emergency cardiac and aortic surgeries. However, in patients using Direct Oral Anticoagulants (DOACs), the administration of Andexanet alfa can induce heparin resistance, complicating management. This study aimed to investigate the mechanisms underlying heparin resistance induced by Andexanet alfa, as well as explore optimal hemostatic strategies for such patients during emergency cardiac and aortic surgeries.

Clause de non-responsabilité: Ce résumé a été traduit à l'aide d'outils d'intelligence artificielle et n'a pas encore été révisé ou vérifié.
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