select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='44938' and ad.lang_id='5' and j.lang_id='5' and vi.lang_id='5'
ISSN: 2329-8901
Angela Amoruso, Francesca Deidda, Marco Pane, Luca Mogna
The human intestinal microbiota may be considered as a post-natally acquired organ composed of a large diversity of bacteria with different functions on human health. Probiotics are widely used to improve gut functionality and immune system responses. The aim of this study was to evaluate the capability of the bacterial strains Bifidobacterium breve BR03 (DSM 16604) and Lactobacillus plantarum LP01 (LMG P-21021) to induce an in vitro immune response in the peripheral blood mononuclear cells (PBMCs) of healthy adult volunteers and to modify the state of oxidative stress and intestinal permeability of in vitro cell models. Specifically, the analysis was conducted on PBMCs after different stimulation times in order to analyze both cells involved in innate immunity and those responsible for acquired immunity and to evaluate the oxidative stress, and on Caco-2 cell line as an intestinal epithelium model.