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A Mono-Articular Septic Arthritis and Multifocal Avascular Necrosis in Absence of Corticosteroid Use: An Unusual Presentation of Primary Antiphospholipid Syndrome

Fatma Fayed

Osteonecrosis (ON) or avascular necrosis results from disruption of blood supply to bone marrow and trabecular bone leading to death of bone. Antiphospholipid Syndrome (APS) may be primary or secondary to other autoimmune disease. The involvement of multiple sites of ON has been documented with APS. Literature suggests that avascular necrosis predispose a septic arthritis in affected joints especially in immunosuppressed patients.