Médecine d'urgence: libre accès
Libre accès

Abstrait

The Use of Hyaluronidase to Treat the Excess of Cross-Linked Hyaluronic Acid Following Aesthetic Medicine Procedures: A Practical Point of View

Evgenyia Ranneva

Polymers formed by hyaluronic acid are generally catalyzed by Hyaluronidase and the product contains oligomers. Hydrolysis of the bond present in between the N-acetyl-Dglucosamine and D-glucuronic acid is responsible for such chemical process. Huge literature support is present supporting the application of this process for reducing cellulitis fibrosis. In the recent times, potential granulomatous reactions are being treated through this process as well as aiding in dissolving excess hyaluronic acid filler. Implication of hyaluronidase includes simple jabbing of hyaluronidase enzyme prepared with sterile solution. Generally, the solution consist sterile lyophilized hyaluronidase preparation with sterile saline medium. After conducting the allergy testing direct injection can be given to the problem area for treatment. Assessment of allergy is mandatory as the enzyme hyaluronidase protein may invoke sensitization in the patient. The expected outcome is mostly rapid and definitive.