Journal de Fertilization: In Vitro - IVF-Worldwide, Médecine de la Reproduction, Génétique & Biologie des Cellules Souches

Journal de Fertilization: In Vitro - IVF-Worldwide, Médecine de la Reproduction, Génétique & Biologie des Cellules Souches
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ISSN: 2375-4508

Abstrait

The Use of Corifollitropin Alfa in Combination with a GnRH Analogue as Final Trigger in the Potential High Responders

Francesco M. Fusi, Mariangela Arnoldi, Rita Secomandi, Laura Zanga, Alessia Galimberti, Enrica Capitanio and Marina Ferrario

Background: A great concern exists in using corifollitropin alfa to induce ovarian stimulation in high responders due to the riskof OHSS.In this study, we utilized corifollitropin alfa in patients with the potential of being high responders, in addition to the GnRH analog triptorelin, as final trigger to induce the oocyte maturation. Intensive luteal support was administered to allow the transfer in the same cycle.

Patients and methods: Between January 2013 and September 2014, 35 patients were stimulated with corifollitropin alfa and underwent in vitro fertilization or intracytoplasmic sperm injection procedures. All women had levels of antimullerian hormone>3 ng/ml and antral follicle count >10 and

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