Cloning & Transgenesis
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The "Evolution" of Mutagenesis

Luigi Mandrich

DNA cloning and mutagenesis are widespread tools in biology. Understanding the structural/functional relationship of the proteins is of great interest, with the aim to clarify the relationships often the researchers used the mutagenic approach. In the last 20 years, several mutagenesis systems have been developed, analyzing them it’s possible to observe the “evolution” of mutagenesis. Here, a short description and differences among three methods widely used of mutagenesis are shown.