Journal d'ophtalmologie clinique et expérimentale
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The Disease Course of Bilateral Endogenous Fungal Endophthalmitis

Zhaohui Yuan, Xiaoyun Liang and Jing Zhong

Purpose: To report the dynamic disease course of a case of bilateral endogenous fungal endophthalmitis, which was successfully treated. Case Report: A 54 year old Chinese man with a history of extracorporeal shock wave lithotripsy (ESWL) and ureteroscopy was referred to our center. After 1 week, his best corrected Snellen visual acuity (BCVA) values were 20/100 and 20/25; the interface between the posterior vitreous face and the retinal surface appeared to be rough in the right eye, and a similar, larger, low-rounded circumscribed apophysis could be observed in the left eye. During the 2nd week, his BCVA values decreased to 20/400 and 20/32. He was diagnosed with bilateral endogenous Candida albicans endophthalmitis after a vitreous biopsy and then underwent binocular pars plana vitrectomy (PPV) with silicone oil injection in both eyes. Postoperatively, his BCVA values were 20/63 and 20/32, and fundoscopy and optical coherence tomography (OCT) showed a regular and smooth interface and retina surface after the removal of the silicone oil at 3 months. Conclusions: We concluded that the rough interface between the posterior vitreous face and the retinal surface is one of the early typical sign of endogenous fungal endophthalmitis, which was treated with PPV with silicone oil injection and antifungal reagents.