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Renal Function in Antiretroviral Treatment (Art) Naive HIV Positive Patients in A Tertiary Care Centre, South India

Ananya Reddy and Rajendra Prasad

Background and objective: Renal disorders are encountered at all stages of HIV infection, and they range from the fluid and electrolyte imbalances commonly seen in hospitalized patients to end-stage renal disease (ESRD). The present study on 30 patients focused on the renal abnormality in ART naïve HIV patients at the time of registration to ART centre. Methods: All HIV positive patients who were not on ART were recruited for the study and checked for renal impairment at the time of registration to the ART centre. Results: A total of 30 patients were screened, of these 22 were males and remaining females. Among the 30 HIV positive patients, 20% ( n = 6) were found to have renal disease with eGFR < 60 ml/min per 1.73 m2, out of which 4 were females. All the 6 patients had CD4 count < 350 cells/cumm and BMI < 20 kg/m2. There was no correlation with urine albumin, microscopy and decreased eGFR. Interpretation and Conclusion: All newly HIV positive patients have to be evaluated for renal abnormalities at the time of diagnosis so that they can be initiated on medication to prolong the onset of HIV associated Nephropathy (HIVAN) and end stage renal disease (ESRD).