Cardiologie clinique et expérimentale
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Neonatal and Childhood Pulmonary Hypertension - An Update (2012)

Matthias Gorenflo, Siegrun Mebus, Ian Adatia, Maria J Cerro, Damien Bonnet and Maurice Beghetti

Although substantial advances have been made in our understanding of pulmonary hypertensive vascular disease there remain important challenges to overcome in designing pediatric drug trials and improving long term survival. We address the current classifications and review the current knowledge on epidemiology, pathogenesis and therapy of pulmonary hypertension.