Sécurité médicale et santé mondiale
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Nano Mat 2020: Formulation of non-ionic surfactant vesicles (NISV) prepared by microfluidics for therapeutic delivery of siRNA into cancer cells- Mohammad Ali Obeid- Yarmouk University, Irbid-Jordan

Mohammad Ali Obeid

RNA interference involves the degradation of a target messenger RNA through the incorporation of short interfering RNAs (siRNA) [1]. The application of siRNA based therapeutics is limited by the development of an effective delivery system. A novel type of nanoparticles known as non-ionic surfactant vesicles (NISV) are commonly used for drug delivery of various therapeutics, are relatively safe and non-expensive, have not been extensively studied for siRNA delivery [2]. Therefore, the aim of this study was to investigate the potential of NISV prepared by microfluidics for siRNA delivery.