Journal d'ophtalmologie clinique et expérimentale
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Mid-Term Results of Filtering Surgery in Corticosteroid-Induced Glaucoma Patients

Jing Fu, Da Peng Mou, Shu Ning Li, Xiao Zhen Wang, Lei Hao and Ning Li Wang

Aim: To analyze the mid-term effect of filtering surgery in patients with corticosteroid-induced glaucoma (CIG).
Methods: This case-series study consisted of 20 eyes of 15 corticosteroid-induced glaucoma patients who received trabeculectomy or non-penetrating trabecular surgery (NPTS) from March 2005 to March 2008. Both preoperative and postoperative intraocular pressure (IOP), cup -disk ratio, Humphrey visual fields, number of glaucoma medications were recorded. Characteristics of postoperative blebs were analyzed with Ultrasound biomicroscope (UBM), and slitlamp. Bleb grading and Ultrasound biomicroscope were performed on all glaucoma surgery eyes at a single final time point.
Results: 14 eyes were performed trabeculectomy, 6 eyes were performed NPTS. Mean IOP before and after trabeculectomy were 30.5±13.1 and 11.4±3.8 mmHg (p<0.01), respectively. Mean IOP before and after NPTS were 20.3±4.7 and 12.2±3.1 mmHg (p<0.01), respectively. The mean vertical cup-disk ratio (VCDR) was 0.54 before surgery compared with 0.55 just after surgery. No significant changes were found in visual fields before and after surgery (P=0.06). According to the outcome of final IOP, success rate was 100%. Based on slit-lamp and Ultrasound biomicroscope evaluation of the bleb, 90% of blebs were functional and 10% were non-functional.
Conclusions: The mid-term glaucoma management in CIG patients undergoing surgery indicated a successful outcome in final IOP and fairly good prognosis for visual function, without antiglaucoma medication.