Plantes Médicinales & Aromatiques
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Abstrait

Medicinal Plants with Potential Antidiabetic Activity and their Assessment

Abdel Nasser Singab, Fadia S Youssef and Mohamed L Ashour

Objective: Diabetes mellitus is a clinical syndrome characterized by a deficiency in insulin production or resistance to insulin action. Consequently, it leads to inappropriate hyperglycemia. Prolonged hyperglycemia can cause severe complications that probably affect every system of the body and every drug taken by the patient. This study highlights the most popular medicinal plants with potential antidiabetic significance, their modes of action together with the method used for their assessment.
Key findings: Through antidiabetic evaluation conducted on different medicinal herbs since centuries revealed the presence of potent antidiabetic activity. Moreover, the candidates from natural source with diverse structures of secondary metabolites. This indicates various sites of action within the human body. Conclusions: Further investigations are required, and more attention should be drawn to explore the biological activity of hundreds of traditionally used medicinal plants both in vitro and in vivo to assess the claimed activity with the aim of finding potent antidiabetic candidates from the natural resources.