Cardiologie clinique et expérimentale
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Mean Platelet Volume is Increased in Patients with Atrial Septal Aneurysm

Mehmet Demir and Canan Demir

Background: Systemic thromboembolism is a serious major complication in patients with Atrial Septal Aneurysm (ASA). However, the pathogenesis of thromboembolism in ASA is not fully understood. The aim of this study was to assess the Mean Platelet Volume (MPV), an indicator of platelet activation, in patients with ASA. Patients and Methods: The study group consisted of 40 patients with ASA. An age, gender, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results: Mean platelet volume was significantly higher among patients with ASA when compared with the control group (9.8 ± 1.1 vs 7.6 ± 0.8 fL, respectively; P < 0.001). Conclusion: We have shown that MPV was significantly elevated in patients with ASA compared to control participant.