Journal des techniques de chromatographie et de séparation
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Lung Cancer and Nicotine

Bharti M and Yashila G

Nicotine present in smoking and tobacco is major cause of occurrence of lung cancer. The basic nature of nicotine helps in easy absorption through lungs. The binding of nicotine and its derivatives to Nicotinic Acetylcholine Receptor results in significant polymorphic mutations in genes coding the subunits of receptors in various populations like Asian and Caucasians which increases the susceptibility of lung cancer in these populations.