Journal d'ophtalmologie clinique et expérimentale
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Long-term Intraocular Pressure Control in a Case of Neovascular Glaucoma Treated with Repeated Intravitreal Bevacizumab Injections

Jayter Silva Paula, Rogério Neri Shinsato, Wilian Silva Queiroz, Jefferson Augusto Santana Ribeiro and Rodrigo Jorge

Ischemic retinopathies may cause neovascular glaucoma due to the growth of fibrovascular tissues which may close the anterior chamber angle and increase intraocular pressure. Angiogenesis factors, such as vascular endothelial growth factor (VEGF), play a fundamental role in the development and maintenance of these diseases. The purpose of this study was to report a case of bilateral neovascular glaucoma secondary to proliferative diabetic retinopathy treated with 16 intravitreal bevacizumab injections (Avastin^®) and followed up for 200 weeks. Adequate intraocular pressure control was observed after bevacizumab injection as well as regression of anterior and posterior segment neovascularization, and maintenance of visual acuity. In the present case, the treatment of neovascular glaucoma with intravitreal bevacizumab was effective for long-term intraocular pressure control although repeated injections were necessary.