Journal d'ophtalmologie clinique et expérimentale
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Long-Term Follow Up of Intra-Retinal Fluid and Outer Retinal Tubulations in a Case of Choroidal Osteoma Following Anti-VEGF Treatment

Khalid H Allam, Reem AlShaikh, Patrik Schatz, Ehab Abdelkader

Purpose: To report long term follow up of intraretinal fluid (IRF) and outer retinal tubulations (ORTs) in a case of choroidal osteoma (CO) over 54 month.

Method: Case report.

Results: A 35 Saudi female presented because of poor vision in her left eye. Her right eye was essentially normal with 20/20 vision (VA). Her left eye had 1/200 VA and showed peripapillary CO involving the macular area. OCT imaging showed intraretinal cystic spaces that were interpreted as a sign of an active choroidal neovascular membrane (CNV). 5 Avastin injections were administered into her left eye with no anatomical or visual improvement. On reviewing her imaging, no CNV was detected at any point. The IRF in this case seems related to RPE damage overlying the CO. ORTs were detected and increased over time.

Conclusion: Clinicians should be careful when assessing cystic spaces in cases of CO. ORTs seem to represent a healing mechanism. IRF and ORTs in CO cases do not seem to benefit from anti-VEGF injections.