Journal de recherche clinique et expérimentale en dermatologie
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Inverted-F Technique: Safety and Optimization Protocol for Collagen Biostimulators

Bruno Bastos*, Carolina Nascimento, Hermes Pretel, Débora Pretto

Purpose: This study aimed to establish criteria associated with the application of Poly-L-Lactic Acid (PLLA) (E_R) in the facial region as a collagen biostimulator. The inverted-F technique was used, consisting of a marking performed for safer and more standardized results.

Methods: Data were collected from 3 female patients. All were submitted to treatment with Poly-L-Lactic Acid (PLLA) (E_R-Rennova Elleva^®-Ghana R&D CO, LTD-South Korea), using the inverted-F technique, according to the individual needs of each patient. Photographic records were taken on the day of application and 60 days after. All data are expressed as mean ± Standard Error of Mean (SEM). All descriptive statistics were performed using the GraphPad Prism 9.0^® software platform (United States).

Results: The data analysis demonstrated that the patients showed an increase in face lifting, greater volumization, and improved vascularity. It is suggested that further studies with a larger sample size be carried out, in order to provide further statistical clarification.

Conclusion: The increase in demand for facial rejuvenation has increased in popularity in recent years. This comprises a non-permanent injectable procedure that is able to restore and improve curves and contours.

Although statistical relevance has not been observed, the inverted-F technique optimizes the use of powerful biostimulators, particularly in patients who look for an accurate aesthetic result, with improved facial curves, lifting in the temporal and zygomatic region, and preserving areas of hyperdynamic muscle movement, as it is a safe and replicable technique.