Journal des troubles du sommeil et de la thérapie
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Hematic Cortisol and Craniofacial Morphology in Children with OSAS

Alberto Caprioglio, Alessandro Ollà, Franca Marino and Luana Nosetti

Study objectives: This study wanted to evaluate the correlations between haematic cortisol levels and the craniofacial morphology in children with Obstructive Sleep Apnoea Syndrome (OSAS) in comparison with healthy children.

Design/setting/patients. This is a case-control study. Children referring to the Paediatric Department, University of Insubria, Varese, in the period between 1st and 31st October 2011 for a history of disturbed sleep were evaluated and 28 children, compliant to our criteria, were enrolled in the study.

Interventions: All patients underwent a full-night polysomnographic evaluation. Haematic cortisol levels were measured using a radioimmunoassay technique. An orthodontic evaluation and a cranial lateral cephalometric analysis were performed.

Measurements and results: Haematic cortisol concentration at 2.00 am was found higher in OSAS patients than in controls (p