Journal international des progrès technologiques
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Hardware Design of a High Speed VLSI Comparator Framework for DNA Sequence Matching Using High Level Synthesis

Dr. Seema Verma , Sanjeev Kumar and Dibyayan Das Sharma

DNA sequence matching has assumed a very important role in molecular biology and bioinformatics. A typical DNA sequence represents a massively huge set of data and hence sequence matching must be made feasible and within practical limits by use of technology and innovation. Here in this paper, a high speed pipelined comparator framework has been designed which can be used for rapid sequence matching. The design is created following a new methodology using GAUT II high level synthesis (HLS) tool which allows developing hardware with optimized performance metrics. The designed hardware has the potential to be a low cost solution to real-time DNA matching and verification processes with significantly low latency.