Journal de recherche clinique et expérimentale en dermatologie
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Genetic Customization of Anti-aging Treatments

Steven Paul Nistico, Ester Del Duca and Flavio Garoia

Skin aging is a multifactorial process that involves both intrinsic factors of genetic and hormonal origin and extrinsic factors of environmental and nutritional nature.
The purpose of this open study on a case series of volunteers is to evaluate the impact of genetic customization of common anti-aging dermocosmetic treatments. We report how the treatment may be customized by acting selectively on the metabolic impairments identified by the analysis of specific DNA variants. The customized cosmetic method shows a significantly higher efficacy compared to non-specific cosmetic treatments such as radiofrequency, suggesting that the combination genetic signature may provide a useful tool for personalized and more effective anti‐aging therapies.