Journal d'ophtalmologie clinique et expérimentale
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Endogenous Fungal Endophthalmitis Developing in a Myasthenia Gravis Individual Treated with High Dose Methylprednisolone

Jia-lin Wang and Yu-ling Liu

Background: To report a successful treatment case of endogenous fungal endophthalmitis caused by corticosteroid impulse therapy and the cultures are always negative for fungi.
Methods: Systemic antifungal treatment and full ophthalmic examination including B-scan ultrasonography, fundus photograph and indocyanine green angiography.
Results: The visual acuity recovered from 0.2 to 0.8. B-scan ultrasonography revealed the largest irregular apophysis which disappeared finally. Both fundus photograph and indocyanine green angiography showed the chorioretinal lesions disappearing.
Conclusion: Endogenous fungal endophthalmitis caused by corticosteroid impulse therapy is noteworthy and under this situation antifungal treatment should be considered even if the culture is negative for fungi.