Anatomie et physiologie : recherches en cours
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Developmental Histogenesis of Human Foetal Vermiform Appendix at Different Gestational Ages 

Mohammad R, Kumar MV, Sreelatha S and Velichety SD

Introduction: Vermiform appendix is a slender projection from caecum, which is not a vestigial organ but is a specialized structure having immunological function.

Aim: The main aim of this study is to assess detailed microscopic features of human fetal vermiform appendix at different gestational ages.

Materials and Methods: For this present study 25 vermiform appendix specimens were collected from the human aborted fetuses of 17-40 weeks gestational ages and both sexes (12 males and 13 females) were studied and appendix were processed for routine histological tissue processing and sectioning and the slides were stained with haematoxylin and eosin.

Results: The wall of the vermiform appendix presented well differentiated 4 layers mucosa, sub mucosa, muscular coat and serosa from 17th week. At 17th week wider lumen and thick wall were observed. Conclusion: Further studies are necessary to elucidate the time of appearance of different types of cells in fetal appendix and their immunological functions.