Médecine interne: libre accès
Libre accès

Abstrait

Cytomegalovirus Antibody Titers in Patients with Bechet's Disease

Oner RI, Sayiner SH and Akgun Sfgfgfgf

Purpose: We aimed to measure the titers of Immunoglobulin G (IgG) formed against latent microbial agents, such as Cytomegalovirus (CMV), in patients with Behcet’s disease (BD) and to compare with healthy population.
Method: Forty-four patients with BD who were or were not receiving immunosuppressive treatment who had their CMV immunoglobulin G (IgG) titers measured and a sixty nine healthy people (control groups) were retrospectively examined. CMV IgG titers in the patients with Behcet’s disease and control groups were compared. Values above the cut-off (cut-off for CMV IgG: 6.00 IU/mL) were regarded as positive.
Findings: At the time of the tests, 18.2% of patients were not receiving any treatment, 40.9% were receiving Colchicum treatment, and 40.9% were receiving immunosuppressive treatment. CMV IgG values were positive in all of our patients and CMV IgG titers were significantly lower in the patient group than in the control group (p=0.012).
Conclusion: CMV may cause serious recurrent infections, particularly in patients who undergo immunosuppressive treatment. In the case of Behcet's disease, determining the initial titration values of CMV infection prior to immunosuppressive treatment may provide an early diagnosis and treatment for recurrent CMV infection.