Cardiologie clinique et expérimentale
Libre accès
ISSN: 2155-9880
ISSN: 2155-9880
Mohammed Saied Mohammed Bakeer
Our understanding to the process of coagulation is based on the classic coagulation cascade, proposed in 1964 by Macfarlane and Davie & Ratnoff. While is considered to be of clinical validity, still many limitations in this model exist. Drugs for anticoagulation based in this model also show the same limitations of the model. Here we review this model and trying to find new concepts as regard this model, with aiming at finding a new way for developing new drugs for manipulating the coagulation system with more favorable profile.