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Brain Metabolic Disturbances in Autism Spectrum Disorder: A systematic Review

Hyuan-seok Kim

Autism spectrum disorder (ASD) is a common neurodevelopmental condition marked by a lack of social contact and a pattern of restricted and repetitive behaviours (RRBs). Neuroimaging studies have revealed a lot about the underlying neurobiological mechanisms of ASD in the last decade. ASD and epilepsy are two neurodevelopmental conditions with a high incidence of comorbidity, implying that they share a similar neurodevelopmental process. However, there is currently no definitive way to determine when a child will inherit either or both syndromes, or to what extent related phenotypes will be affected. The current review presents brain imaging research to classify the brains of people with ASD over the lifespan.