Anatomie et physiologie : recherches en cours
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Blood Ions and Total Calcium in Dairy Cows: A Correlation Paradox

Abdulkerim Deniz

This review introduced shortly blood Ionised Calcium (IC), Total Calcium (TCA) and their association with clinical and subclinical hypocalcemia in dairy cows. Calcium receptors in the parathyroid cells inactivate when serum calcium levels fall, triggering an increase in PTH secretion. This increase in PTH balances serum calcium by activating the parathyroid receptors in the bones and kidneys, increasing overall calcium resorption. In the kidney, increased PTH secretion enhances calcium-restorative effects by increasing secretion of 1,25-dihydroxyvitamin D (1.25D), the vitamin D receptor in the gut, and increases active calcium absorption by the bone Furthermore, the paradox between IC and TCA correlation and their threshold values for hypocalcemia were discussed.