Journal de protéomique et bioinformatique

Journal de protéomique et bioinformatique
Libre accès

ISSN: 0974-276X

Abstrait

A Python Based Hydrophilicity Plot to Assess the Exposed and Buried Regions of a Protein

P. Pandarinath, A. Appa Rao and G. Lavanya Devi

Predicting the antigenic regions of a protein is of prime importance in assessing the states of a polypeptide chain as exposed or buried regions. This can be achieved by calculating and plotting the hydrophilicity of a protein using values of Hoop-Woods scale. Hence, in this paper, we report a hydrophilicity plot of Hoop-Woods scale amino acid sequence of a protein on its x-axis, and degree of hydrophobicity or hydrophilicity on its y-axis using python language as architecture by utilizing various functional attributes such as scipy, matplot and numpy modules. A case study has been reported using siallidase-4 enzyme. The program code can be available on request.

Clause de non-responsabilité: Ce résumé a été traduit à l'aide d'outils d'intelligence artificielle et n'a pas encore été révisé ou vérifié.
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