Journal des soins pharmaceutiques et des systèmes de santé
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Abstrait

InforMatrix Aromatase Inhibitors in Breastcancer

Janknegt R

The InforMatrix method was applied to aromatase inhibitors. The following selection criteria were used: clinical efficacy, safety, tolerability, ease of use (from a patient’s perspective), applicability (from a caregiver’s perspective) and cost. All three available aromatase inhibitors were included: anastrozole, letrozole and exemestane. The InforMatrix method provides the user with all relevant clinical information concerning the medicines. By assigning a weight to both the selection criteria and judging the performance of the medicines on each criterion a personal selection of the most suitable medicines is made, which serves as the starting point for a concrete discussion in the formulary committee.