Journal du métabolisme des médicaments et de la toxicologie
Libre accès
ISSN: 2157-7609
ISSN: 2157-7609
S Harshitha, R surya santhosh, SK. Baba Hussain, K S Natraj, A Srinivasa rao
Hydrophilic interaction liquid chromatography (HILIC) is a variant of normal phase liquid chromatography provides that partly overlaps with other chromatographic applications such as ion chromatography and reverse phase liquid chromatography a way to separate small polar compounds on polar stationary phases effectively. The purpose of this work was to review the characterization of HILIC stationary phases and their applications and its column chemistry and also method development as HILIC increases the scope of possible applications of liquid chromatography.